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The LCGC Blog: Useful Tips for GC-MS

Date: Thu, 2015-03-19 (All day)Publish Start Date: Mon, 2015-03-16 (All day)Article sort author:  workspace://SpacesStore/97d4e7e5-fb8a-48fc-92ae-613e6feb3bbf read more

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A New Consortium of Researchers for Environmental Analysis and Remediation

Date: Thu, 2015-04-09 (All day)Article sort author:  workspace://SpacesStore/48884ff7-f025-4ceb-81f3-5819c866a2fd read more

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The LCGC Blog: Four Steps to Troubleshooting an HPLC Problem

What if we could make the troubleshooting poster on the laboratory wall come to life? What if we could build an engine which figured out the most likely causes of groups of symptoms and offer these up...

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The LCGC Blog: A Disconnect Between Science Research and Science Education...

Date: Tue, 2015-05-12 (All day)Article sort author:  workspace://SpacesStore/48884ff7-f025-4ceb-81f3-5819c866a2fd read more

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The LCGC Blog: Troubleshooting Retention Time Issues in Reversed Phase HPLC

I got into a discussion with a learned colleague recently regarding the relationship between peak height and flow rate in gradient HPLC. We haven't really resolved the discussion, there are suggestions...

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The LCGC Blog: Forensics, Lawyers, and Method Validation—Surprising Knowledge...

Date: Mon, 2015-06-08 (All day)Publish Start Date: Mon, 2015-06-08 (All day)Article sort author:  workspace://SpacesStore/48884ff7-f025-4ceb-81f3-5819c866a2fd read more

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The LCGC Blog: Why Every Good Analytical Chemist Also Needs to Be a Statistician

Date: Mon, 2015-06-15 (All day)Publish Start Date: Mon, 2015-06-15 (All day)Article sort author:  workspace://SpacesStore/97d4e7e5-fb8a-48fc-92ae-613e6feb3bbf read more

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Eight Steps to Better Results from Solid-Phase Extraction

If you use SPE in your work, then most likely it’s very important to the success of your applications and it’s proper implementation will be key to the performance of your analyses. However, SPE...

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Paired Ion Electrospray Ionization for Trace Anion Analysis

Date: Tue, 2015-07-14 (All day)Publish Start Date: Tue, 2015-07-14 (All day)Article sort author:  workspace://SpacesStore/48884ff7-f025-4ceb-81f3-5819c866a2fd read more

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The LCGC Blog: The Environmental Effects of Unconventional Drilling: Why We...

Date: Tue, 2015-08-11 (All day)Publish Start Date: Tue, 2015-08-11 (All day)Article sort author:  workspace://SpacesStore/48884ff7-f025-4ceb-81f3-5819c866a2fd read more

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How to Estimate Error in Calibrated Instrument Methods—And Why We Have...

When was the last time you reported your results with an estimate of the error associated with the data? You don’t need to because your method is performing within the levels defined by various...

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The LCGC Blog: An Open Inquiry Model for Science Education

There is a shortcoming in our current educational system. There is too much rote learning, and not enough time given to let science-minded students explore a topic. Overall, when students ask their own...

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The Acid Test - More Useful Calculations for HPLC Eluent Preparation

Useful equations to improve the robustness of your separations.Date: Mon, 2015-09-14 (All day)Publish Start Date: Mon, 2015-09-14 (All day)Article sort author:...

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The LCGC Blog: New On-Line Sample Preparation and Analysis Combinations...

If you want to improve analytical methods to make them better, the sample preparation step is probably one of the best steps to target.Date: Wed, 2015-10-07 (All day)Publish Start Date: Tue, 2015-10-06...

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The LCGC Blog: Simple Visual Methods to Assess HPLC Column Performance – and...

A client asked me recently for a quick but "as optimized as possible" separation for some monoclonal antibody (MAb) characterization (digest) samples using LC-MS. The samples had been prepared and were...

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The LCGC Blog: Column Overload in Gas Chromatography with Vacuum Ultraviolet...

Column overload is a very commonly encountered issue in GC for beginners. Changes in peak symmetry, generally observed as peak fronting, can be subtle in the sharp peaks generated by GC, but the result...

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The LCGC Blog: GC Troubleshooting in 20 Pictures (Part 1)

They say a picture paints a thousand words… This month I’ve taken inspiration from a recent webcast, presented at www.chromacademy.com, in which I presented real data from our work that represents some...

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The LCGC Blog: Why Column Screening Is Better than Mobile-Phase Screening for...

It is much more efficient to screen column chemistries to achieve optimum separations for a set of target analytes, than it is to play with different mobile-phase conditions on a single column. Kevin...

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In Defense of Nitrogen as a Carrier for Capillary GC

There has been much written about the use of nitrogen as a carrier gas for capillary GC. Formerly, to say it wasn’t any good. Latterly to say that it’s pretty good and a better alternative to Helium...

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An Italian Sabbatical to Bring 2D Chromatography to Texas

After 10 years at U.T. Arlington, I have decided it is time to take one of the best opportunities afforded to researchers in an academic faculty position—to travel abroad and assimilate new techniques...

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